Manufacturer: AFT Pharmaceuticals Ltd, NZ manufactures Desmopressin PH&T Nasal Spray.

Uses:

The uses of Desmopressin PH&T Nasal Spray include:
Desmopressin is used in people with certain bleeding problems (hemophilia A, type 1 von Willebrand's disease) to control bleeding caused by surgery, injuries, or heavy menstrual periods. This medication is a man-made form of a certain substance in the body called vasopressin that helps with normal blood clotting.

Indication:

DESMOPRESSIN PH&T nasal spray solution is indicated for the treatment of cranial diabetes insipidus and for establishing renal concentration capacity testing.

DESMOPRESSIN PH&T nasal spray solution is also indicated for the treatment of primary nocturnal enuresis in patients (from 5 years of age) with normal ability to concentrate urine.

Dosage and Administration:

1 dose of the spray provides 0.1ml, which corresponds to 10g desmopressin acetate.

Cranial diabetes insipidus

Dosage is individual after testing, but normal dosage for adults is 10-20g 1-2 times daily. For children 5-10g 1-2 times daily. In the event of signs of water retention/hyponatremia treatment should be interrupted and the dose should be adjusted.

Primary nocturnal enuresis

A clinically effective dose is individual and may vary from 10 to 40g administered intranasally. A suitable initial dose is 20g intranasally at bedtime. Fluid restriction should be observed, please see under Warnings and Precautions. In the event of signs of water retention/hyponatremia treatment should be interrupted. Assessment of the necessity of continued treatment should be made after three months during one substance-free week.