The uses of Locoid Cream - Hydrocortisone include: Hydrocortisone is available with or without a prescription. Low-strength preparations (0.5% or 1%) are used without a prescription for the temporary relief of
(1) minor skin irritations, itching, and rashes caused by eczema, insect bites, poison ivy, poison oak, poison sumac, soaps, detergents, cosmetics, and jewelry;
(2) itchy anal and rectal areas; and
(3) itching and irritation of the scalp. It is also used to relieve the discomfort of mouth sores.