Manufacturer: Schering-Plough manufactures Ovestin Vaginal Cream.
The uses of Ovestin Vaginal Cream include:
Atrophy of the lower urogenital tract related to oestrogen deficiency, notably
1.For the treatment of vaginal complaints such as dyspareunia, dryness and itching.
for the prevention of recurrent infections of the vagina and lower urinary tract.
2.In the management of micturition complaints (such as frequency and dysuria) and mild urinary incontinence.
Pre- and postoperative therapy in postmenopausal women undergoing vaginal surgery.
3.Climacteric complaints such as hot flushes and night sweating.
4.A diagnostic aid in case of a doubtful atrophic cervical smear.
5.Infertility due to cervical hostility.
Dosage And Administration:
Atrophy of the lower urogenital tract
1 application per day for the first weeks, followed by a gradual reduction, based on relief of symptoms, until a maintenance dosage (e.g. 1 application twice a week) is reached.
Pre- and post-operative therapy in postmenopausal women undergoing vaginal surgery
1 application per day in the 2 weeks before surgery; 1 application twice a week in the 2 weeks after surgery.
A diagnostic aid in case of a doubtful atrophic cervical smear
1 application on alternate days in the week before taking the next smear.
OVESTIN cream should be administered intravaginally by means of a calibrated applicator before retiring at night.
One application (applicator filled to the red mark) contains 0.5g OVESTIN cream which corresponds to 0.5mg oestriol.
Instructions For Use For The Patient
Remove cap from the tube, invert it, and use the sharp point to open the tube.
Screw the end of the applicator onto the tube.
Squeeze tube to fill the applicator with the cream until the plunger stops.
Unscrew applicator from tube and replace cap on tube.
To apply cream, lie down, insert end of applicator deep into the vagina.
Slowly push plunger all the way in until applicator is empty.
After use, pull plunger out of barrel and wash both in warm, soapy water. Do not use detergents. Rinse well afterwards.
DO NOT PUT THE APPLICATOR IN HOT OR BOILING WATER.
A missed dose should be administered as soon as remembered, unless the missed dose is noticed at the day of the next dose. In the latter case the missed dose should be skipped and the regular dosing scheme continued. Two doses must never be administered on the same day.
For initiation and continuation of treatment of postmenopausal symptoms, the lowest effective dose for the shortest duration of time should be used (see Warnings and Precautions).
In women not taking HRT or women who switch from a continuous combined HRT product, treatment with OVESTIN may be started on any day. Women who switch from cyclic HRT regimen should start OVESTIN treatment one week after completion of the cycle.