The uses of RECLIDE include: Insulin is produced by the pancreas and is the main hormone responsible for controlling sugar levels in the blood. It normally makes the cells of the body remove excess sugar from the blood.
People with type 2 diabetes (non-insulin dependent diabetes) have a deficiency of insulin, and the cells of their bodies are also resistant to the action of insulin. This means that blood sugar levels can become too high.
Gliclazide is a type of antidiabetic medicine known as a sulphonylurea. It is used to help lower blood sugar in people with type 2 diabetes. It works by acting on the cells in the pancreas that produce insulin. These cells are called beta cells, and gliclazide causes them to produce more insulin.
Gliclazide improves insulin production immediately after eating. This is called early or first phase insulin secretion, and does not normally happen in people with type 2 diabetes. The enhanced insulin production results in a blood sugar lowering effect in response to meals or glucose, as occurs naturally in non-diabetic people.
Gliclazide is used when dietary measures, weight loss and physical exercise are not enough to lower blood sugar levels in type 2 diabetes. Gliclazide has been shown to prevent blood cells called platelets from clumping together in the blood. It also increases the breakdown of blood clots that form within the blood vessels. This may help prevent the long-term complications of diabetes, which may be partly due to changes in the blood vessels caused by these mechanisms.