The uses of TOPAMAC include: Topiramate is used alone or with other medications to treat certain types of seizures in people who have epilepsy.
Topiramate is also used with other medications to control seizures in people who have Lennox-Gastaut syndrome (a disorder that causes seizures and developmental delays).
Topiramate is used to treat patients who continue to have seizures even when they take other anti-seizure medications.
Topiramate is also used to prevent migraine headaches, but not to relieve the pain of migraine headaches when they occur. Topiramate is in a class of medications called anticonvulsants. It works by decreasing abnormal excitement in the brain.