Manufacturer: Novo Nordisk manufactures Vagifem Vaginal.


The uses of Vagifem Vaginal include:

Vagifem is indicated for the treatment of atrophic vaginitis due to oestrogen deficiency.

Dosage and Administration

Vagifem is administered deeply into the vagina using the applicator.

Initial dose: 1 vaginal tablet a day for two weeks

Maintenance dose: 1 vaginal tablet twice a week.

Treatment may be started on any convenient day.

If a dose is forgotten, it should be taken as soon as the patient remembers. A double dose should be avoided.

For initiation and continuation of treatment of postmenopausal symptoms, the lowest effective dose for the shortest duration should be used (see Warnings and Precautions).

Vagifem may be used in women with or without an intact uterus.

During treatment especially during the first 2 weeks minimal absorption may be seen but as plasma oestradiol levels after the first 2 weeks usually do not exceed postmenopausal levels the addition of a progestagen is not recommended.


Open the blister pack at the plunger end.

Insert the applicator in the vagina until resistance is met (8-10 cm).

Release the tablet by pressing the plunger.

Withdraw the applicator and discard.